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Change your Gut with Vitamin D – Thomas DeLauer
The resulting lack of pantothenic acid adversely affects the immune system, producing a “pro-inflammatory” state associated with atherosclerosis and autoimmunity.
Vitamin D and B100 were recommended to over 1000 neurology patients. Sleep characteristics, pain levels, neurologic symptoms, and bowel complaints were recorded by the author at routine appointments.
Three months of vitamin D plus B100 resulted in improved sleep, reduced pain and unexpected resolution of bowel symptoms.
This often-misunderstood “vitamin” is not a vitamin — it is a prohormone. Prohormones are substances that the body converts to a hormone.
It is required to absorb calcium from the gut into the bloodstream.
Vitamin D is mostly produced in the skin in response to sunlight and is also absorbed from food eaten (about 10% of vitamin D is absorbed this way) as part of a healthy balanced diet.
The liver and kidneys convert vitamin D (produced in the skin and taken up in the diet), into the active hormone, which is called calcitriol.
When the stomach sphincter is weak the acid moves up into the esophagus, where it doesn’t belong, causing acid reflux.
The D we make on our skin goes to the liver, then into the bile, it keeps the bile acids dissolved, preventing gallstones from forming.
Because there are D receptors in the islet cells of the pancreas that make insulin, not enough D may contribute to the development of diabetes.
Low vitamin D is related to poor stomach emptying as well as bloating and constipation or “irritable bowel”.
The irritable bowel may result from losing our “happy, helpful” bacteria in our lower GI tract. They die off when we don’t supply the vitamin D the bacteria also need to survive.
The vitamin D receptor plays a critical role in mucosal barrier homeostasis by preserving the integrity of junction complexes and the healing capacity of the colonic epithelium.
Therefore, vitamin D deficiency may compromise the mucosal barrier, leading to increased susceptibility to mucosal damage and increased risk of IBD (inflammatory bowel disease).
Vitamin D is said to be a key player in holding the tight junctions of the intestinal lining together, which means deficiency could actually contribute to the onset of leaky gut.
1) Vitamin D: Fundamental to Sleep and Digestive Health | Judy Tsafrir, M.D. (2014, September 1). Retrieved from https://www.judytsafrirmd.com/vitamin-d-fundamental-to-sleep-and-digestive-health/
2) Vitamin D | You and Your Hormones from the Society for Endocrinology. (n.d.). Retrieved from http://www.yourhormones.info/hormones/vitamin-d/
3) Kong J , et al. (n.d.). Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier. – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/17962355
4) SC, G. (n.d.). Vitamin D deficiency changes the intestinal microbiome reducing B vitamin production in the gut. The resulting lack of pantothenic acid adversely a… – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/27515213
5) Effects of vitamin D supplementation on intestinal permeability, cathelicidin and disease markers in Crohn’s disease: Results from a randomised double-blind placebo-controlled study – Tara Raftery, Adrian R Martineau, Claire L Greiller, Subrata Ghosh, Deirdre McNamara, Kathleen Bennett, Jon Meddings, Maria O’Sullivan, 2015. (2015, February 11). Retrieved from http://journals.sagepub.com/doi/full/10.1177/2050640615572176?hootPostID=dea4f36d012aa0cf6b438dff161236a5&
6) Vitamin D Associated with Reduced Intestinal Permeability. (2018, March 13). Retrieved from https://realfoodforager.com/vitamin-d-associated-with-reduced-intestinal-permeability-and-extended-remission-in-autoimmunity/
7) Vitamin D and mucosal immune function. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955835/
8) Mucosal T cells in gut homeostasis and inflammation. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976609/
9) Vitamin D | Hormone Health Network. (n.d.). Retrieved from https://www.hormone.org/hormones-and-health/hormones/vitamin-d