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Change your Gut with Vitamin D – Thomas DeLauer

The resulting lack of pantothenic acid adversely affects the immune system, producing a “pro-inflammatory” state associated with atherosclerosis and autoimmunity.

Vitamin D and B100 were recommended to over 1000 neurology patients. Sleep characteristics, pain levels, neurologic symptoms, and bowel complaints were recorded by the author at routine appointments.

Three months of vitamin D plus B100 resulted in improved sleep, reduced pain and unexpected resolution of bowel symptoms.

This often-misunderstood “vitamin” is not a vitamin — it is a prohormone. Prohormones are substances that the body converts to a hormone.

It is required to absorb calcium from the gut into the bloodstream.

Vitamin D is mostly produced in the skin in response to sunlight and is also absorbed from food eaten (about 10% of vitamin D is absorbed this way) as part of a healthy balanced diet.

The liver and kidneys convert vitamin D (produced in the skin and taken up in the diet), into the active hormone, which is called calcitriol.

When the stom­ach sphinc­ter is weak the acid moves up into the esoph­a­gus, where it doesn’t belong, caus­ing acid reflux.

The D we make on our skin goes to the liver, then into the bile, it keeps the bile acids dis­solved, pre­vent­ing gallstones from form­ing.

Because there are D recep­tors in the islet cells of the pan­creas that make insulin, not enough D may con­tribute to the devel­op­ment of dia­betes.

Low vit­a­min D is related to poor stom­ach emp­ty­ing as well as bloat­ing and con­sti­pa­tion or “irri­ta­ble bowel”.

The irri­ta­ble bowel may result from los­ing our “happy, help­ful” bac­te­ria in our lower GI tract. They die off when we don’t sup­ply the vit­a­min D the bac­te­ria also need to sur­vive.

The vitamin D receptor plays a critical role in mucosal barrier homeostasis by preserving the integrity of junction complexes and the healing capacity of the colonic epithelium.

Therefore, vitamin D deficiency may compromise the mucosal barrier, leading to increased susceptibility to mucosal damage and increased risk of IBD (inflammatory bowel disease).

Vitamin D is said to be a key player in holding the tight junctions of the intestinal lining together, which means deficiency could actually contribute to the onset of leaky gut.

References

1) Vitamin D: Fundamental to Sleep and Digestive Health | Judy Tsafrir, M.D. (2014, September 1). Retrieved from https://www.judytsafrirmd.com/vitamin-d-fundamental-to-sleep-and-digestive-health/
2) Vitamin D | You and Your Hormones from the Society for Endocrinology. (n.d.). Retrieved from http://www.yourhormones.info/hormones/vitamin-d/
3) Kong J , et al. (n.d.). Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier. – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/17962355
4) SC, G. (n.d.). Vitamin D deficiency changes the intestinal microbiome reducing B vitamin production in the gut. The resulting lack of pantothenic acid adversely a… – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/27515213
5) Effects of vitamin D supplementation on intestinal permeability, cathelicidin and disease markers in Crohn’s disease: Results from a randomised double-blind placebo-controlled study – Tara Raftery, Adrian R Martineau, Claire L Greiller, Subrata Ghosh, Deirdre McNamara, Kathleen Bennett, Jon Meddings, Maria O’Sullivan, 2015. (2015, February 11). Retrieved from http://journals.sagepub.com/doi/full/10.1177/2050640615572176?hootPostID=dea4f36d012aa0cf6b438dff161236a5&
6) Vitamin D Associated with Reduced Intestinal Permeability. (2018, March 13). Retrieved from https://realfoodforager.com/vitamin-d-associated-with-reduced-intestinal-permeability-and-extended-remission-in-autoimmunity/
7) Vitamin D and mucosal immune function. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955835/
8) Mucosal T cells in gut homeostasis and inflammation. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976609/
9) Vitamin D | Hormone Health Network. (n.d.). Retrieved from https://www.hormone.org/hormones-and-health/hormones/vitamin-d

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