Liver Health: 4 Worst Damaging Habits- Thomas DeLauer… http://www.ThomasDeLauer.com for all your business, health, and fitness answers. The number one over the counter medication responsible for wrecking our livers is acetaminophen. Join Celebrity Trainer, Author & Organic Foods Expert, Thomas DeLauer to find out what other habits may be contributing to the health and function of our livers. Learn how the liver plays a big role in our metabolism, how we burn fat, how we get into shape, and detoxification.
1) Too much self-medication:
One of the main functions of the liver is to break down substances that we take by mouth, including medications, herbs and supplements. This process usually takes place efficiently and without causing any harm. When new medications are developed, they are extensively tested to make sure they are safe before being approved for general use. Acetaminophen, when used as directed, is extremely safe even for people with liver disease. However, taking too much acetaminophen at once, or taking a high dose of acetaminophen continuously over several days can cause damage to the liver.
How it Damages the Liver: A dose of Tylenol is absorbed by the gastrointestinal system and released into the bloodstream, where it alleviates pain and symptoms of fever. The liver filters the blood, which is responsible for metabolizing Tylenol into compounds that can be excreted by the body. About 90% is metabolized into harmless substances and excreted in the urine by the kidneys. Another 2% is removed without being metabolized. Between 5-10% is metabolized into a toxic compound called N-acetyl-p-benzoquinoeimine (NAPQI). Normally, the liver can safely remove NAPQI by combining it with gluthathione and converting it into a water-soluble product that is excreted in bile. However, after an overdose, the liver does not have enough gluthathione to combine with the NAPQI. Excess amounts of the toxic chemical cause rapid cell death, necrosis, tissue damage, and potentially deadly acute liver failure. (1,2,3)
2) Alcohol abuse:
The liver can only handle a certain amount of alcohol at any given time, so if you drink more than the liver can deal with by drinking too quickly, or drinking too much, your liver cells struggle to process it. When alcohol reaches the liver, it produces a toxic enzyme called acetaldehyde, which can damage liver cells and cause permanent scarring.
Though cigarette smoke does not directly come into contact with the liver, it does indirectly affect the liver. The chemicals in cigarette smoke eventually make their way to the liver. These chemicals cause oxidative stress on the liver, which leads to damage to the liver cells and fibrosis. Oxidative stress is involved in the aging of all the organs of the body. Oxidation produces free radicals that damage the cells of the body.
4) Lack of Sleep:
If you want to keep your body — and particularly your liver – in good condition, it is important that you get enough sleep. During sleep, the body repairs and renews its cells, so lack of sleep will interfere with that. In turn, if the liver cannot repair and renew itself as you sleep, it can’t function properly when you’re awake. A study published in the Journal of Anatomy found that sleep deprivation can cause oxidative stress to the liver. It was found that livers weren’t processing fat efficiently and instead allowed fat to accumulate (which proves that the body cannot function well without a properly working liver) (8)
1) Acetaminophen and Liver Injury: Q & A for Consumers. (n.d.). Retrieved from http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm168830.htm
2) How Does Tylenol Cause Liver Damage? (n.d.). Retrieved from https://www.schmidtlaw.com/how-does-tylenol-cause-liver-damage/
3) How Does Tylenol Cause Liver Damage? (n.d.). Retrieved from https://www.schmidtlaw.com/how-does-tylenol-cause-liver-damage/
4) Maher, J. (1997). Exploring Alcohol’s Effects on Liver Function. Retrieved from https://pubs.niaaa.nih.gov/publications/arh21-1/05.pdf
5) Alcohol — Love Your Liver. (n.d.). Retrieved from http://loveyourliver.com.au/alcohol/
6) Heavy smoking and liver. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088100/
7) 5 Common Habits That Damage Your Liver. (n.d.). Retrieved from http://www.healthyandnaturalworld.com/common-habits-that-damage-your-liver/
8) Sleep deprivation predisposes liver to oxidative stress and phospholipid damage: a quantitative molecular imaging study. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408992/
9) Liver Health: The Role of Turmeric in Fatty Liver Disease. (n.d.). Retrieved from http://www.globalhealingcenter.com/natural-health/turmeric-and-fatty-liver-disease/
10) Turmeric Can Reduce Risk of Fatty Liver Disease. (n.d.). Retrieved from https://hepfree.nyc/turmeric-can-reduc-e/