Vitamin C is WORTHLESS without Vitamin D | Bio Hacks to Look and Feel Your Best- Thomas DeLauer

Vitamin C is WORTHLESS without Vitamin D | Bio Hacks to Look and Feel Your Best- Thomas DeLauer



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Vitamin C is WORTHLESS without Vitamin D | Bio Hacks to Look and Feel Your Best- Thomas DeLauer. In this video, Thomas will dive into the relationship between Vitamin C and Vitamin D and explain why it is that when they are combined, the real magic happens.

Vitamin C & Immune Cells:
Vitamin C produces beneficial effects on virtually all of the immune system’s cells-

Natural killer (NK) cells: NK cells move in on infectious and malignant targets – Vitamin C helps NK cells track and destroy tumor cells as well by reducing the shielding effect of platelets (blood clotting cell fragments) that would prevent NK cells from destroying them.

Neutrophils: are the main immune system cell for fighting bacterial infections. Neutrophils engulf invading organisms, then destroy them with powerful blasts of short-lived oxygen free radicals. Vitamin C supports many aspects of neutrophil function, aiding in their ability to chase down bacterial targets and improving their ability to engulf and kill such targets.

Lymphocytes: are immune system cells that produce antibodies (called B-lymphocytes) and coordinate with other immune cells to guide them towards threats needing destruction. When they detect a threat, lymphocytes rapidly reproduce in a proliferative response that is enhanced in the presence of vitamin C.

Vitamin D & T Cells:
For T cells to detect and kill foreign pathogens such as clumps of bacteria or viruses, the cells must first be ‘triggered’ into action and ‘transform’ from inactive immune cells into killer cells that are primed to seek out and destroy foreign pathogens. T cells rely on vitamin D in order to activate and they would remain dormant, ‘naïve’ to the possibility of threat if vitamin D is lacking in the blood. When a T cell is exposed to a foreign pathogen, it extends a signaling device (vitamin D receptor) with which it searches for vitamin D. This means that the T cell must have vitamin D or activation of the cell will cease – if the T cells cannot find enough vitamin D in the blood, they won’t even begin to mobilize.

T cells that are successfully activated transform into one of two types of immune cell:
They either become killer cells that will attack foreign pathogens or they become helper cells that send messages to the immune system, passing on knowledge about the pathogen so that the immune system can recognize and remember it at their next encounter. It was found that while Vitamin C deficiency “potentiated effects of Vitamin D deprivation and impaired a restorative action of Vitamin D.”

References:
1) Forrest KY and Stuhldreher WL. (n.d.). Prevalence and correlates of vitamin D deficiency in US adults. – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/21310306

2) Vitamin D crucial to activating immune defenses. (2018, March 12). Retrieved from https://www.sciencedaily.com/releases/2010/03/100307215534.htm

3) Vitamin D and the Immune System. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166406/

4) Urashima M , et al. (n.d.). Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren. – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/20219962

5) Ströhle A and Hahn A. (n.d.). [Vitamin C and immune function]. – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/19263912

6) Carr AC and Maggini S. (n.d.). Vitamin C and Immune Function. – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/29099763

7) Vitamin C and Optimal Immunity | Life Extension Magazine. (n.d.). Retrieved from https://www.lifeextension.com/magazine/2015/11/the-link-between-vitamin-c-and-optimal-immunity/page-01

8) A short overview of vitamin C and selected cells of the immune system. (n.d.). Retrieved from https://link.springer.com/article/10.2478/s11536-010-0066-x

9) Johnston CS , et al. (n.d.). Vitamin C supplementation slightly improves physical activity levels and reduces cold incidence in men with marginal vitamin C status: a randomized… – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/25010554

10) Vitamin C and Immune Function. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707683/

11) Sergeev IN , et al. (n.d.). Ascorbic acid effects on vitamin D hormone metabolism and binding in guinea pigs. – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/2170601

12) Cantatore FP , et al. (n.d.). The importance of vitamin C for hydroxylation of vitamin D3 to 1,25(OH)2D3 in man. – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/1655350

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